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Exosome secretion from hypoxic cancer cells reshapes the tumor microenvironment and mediates drug resistance

Hypoxia is a common phenomenon in solid tumors as the poorly organized tumor vasculature cannot fulfill the increasing oxygen demand of rapidly expanding tumors. Under hypoxia, tumor cells reshape their microenvironment to sustain survival, promote metastasis, and develop resistance to therapy. Exos...

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Detalles Bibliográficos
Autores principales: To, Kenneth K. W., Cho, William C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511811/
https://www.ncbi.nlm.nih.gov/pubmed/36176760
http://dx.doi.org/10.20517/cdr.2022.38