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Exosome secretion from hypoxic cancer cells reshapes the tumor microenvironment and mediates drug resistance
Hypoxia is a common phenomenon in solid tumors as the poorly organized tumor vasculature cannot fulfill the increasing oxygen demand of rapidly expanding tumors. Under hypoxia, tumor cells reshape their microenvironment to sustain survival, promote metastasis, and develop resistance to therapy. Exos...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OAE Publishing Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9511811/ https://www.ncbi.nlm.nih.gov/pubmed/36176760 http://dx.doi.org/10.20517/cdr.2022.38 |