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Evolutionary History and Strength of Selection Determine the Rate of Antibiotic Resistance Adaptation

Bacterial adaptation to stressful environments often produces evolutionary constraints whereby increases in resistance are associated with reduced fitness in a different environment. The exploitation of this resistance-cost trade-off has been proposed as the basis of rational antimicrobial treatment...

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Detalles Bibliográficos
Autores principales: Cisneros-Mayoral, Sandra, Graña-Miraglia, Lucía, Pérez-Morales, Deyanira, Peña-Miller, Rafael, Fuentes-Hernández, Ayari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512152/
https://www.ncbi.nlm.nih.gov/pubmed/36062982
http://dx.doi.org/10.1093/molbev/msac185