Bone marrow adipocytes drive the development of tissue invasive Ly6C(high) monocytes during obesity

During obesity and high fat-diet (HFD) feeding in mice, sustained low-grade inflammation includes not only increased pro-inflammatory macrophages in the expanding adipose tissue, but also bone marrow (BM) production of invasive Ly6C(high) monocytes. As BM adiposity also accrues with HFD, we explored...

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Detalles Bibliográficos
Autores principales: Boroumand, Parastoo, Prescott, David C, Mukherjee, Tapas, Bilan, Philip J, Wong, Michael, Shen, Jeff, Tattoli, Ivan, Zhou, Yuhuan, Li, Angela, Sivasubramaniyam, Tharini, Shi, Nancy, Zhu, Lucie Y, Liu, Zhi, Robbins, Clinton, Philpott, Dana J, Girardin, Stephen E, Klip, Amira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512398/
https://www.ncbi.nlm.nih.gov/pubmed/36125130
http://dx.doi.org/10.7554/eLife.65553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512398/
https://www.ncbi.nlm.nih.gov/pubmed/36125130
http://dx.doi.org/10.7554/eLife.65553

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