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The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron tomography, and proteomics revealed that it i...

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Detalles Bibliográficos
Autores principales: Villalta, Alejandro, Schmitt, Alain, Estrozi, Leandro F, Quemin, Emmanuelle RJ, Alempic, Jean-Marie, Lartigue, Audrey, Pražák, Vojtěch, Belmudes, Lucid, Vasishtan, Daven, Colmant, Agathe MG, Honoré, Flora A, Couté, Yohann, Grünewald, Kay, Abergel, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512402/
https://www.ncbi.nlm.nih.gov/pubmed/35900198
http://dx.doi.org/10.7554/eLife.77607