Engineered Hybrid Treg-Targeted Nanosomes Restrain Lung Immunosuppression by Inducing Intratumoral CD8(+)T Cell Immunity

INTRODUCTION: Tumor immunotherapy is a key therapeutic paradigm for the treatment of several malignancies. However, in metastatic lung cancer, classical immunotherapy regimes are ineffective due to regulatory T cell (Treg)-related immunosuppression and tumor relapse. MATERIALS: To address this issue...

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Detalles Bibliográficos
Autores principales: Domvri, Kalliopi, Petanidis, Savvas, Zarogoulidis, Paul, Anestakis, Doxakis, Charalampidis, Charalampos, Tsavlis, Drosos, Huang, Haidong, Freitag, Lutz, Hohenforst-Schmidt, Wolfgang, Matthaios, Dimitris, Katopodi, Theodora, Porpodis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512414/
https://www.ncbi.nlm.nih.gov/pubmed/36172007
http://dx.doi.org/10.2147/IJN.S346341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512414/
https://www.ncbi.nlm.nih.gov/pubmed/36172007
http://dx.doi.org/10.2147/IJN.S346341

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