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Engineered Hybrid Treg-Targeted Nanosomes Restrain Lung Immunosuppression by Inducing Intratumoral CD8(+)T Cell Immunity
INTRODUCTION: Tumor immunotherapy is a key therapeutic paradigm for the treatment of several malignancies. However, in metastatic lung cancer, classical immunotherapy regimes are ineffective due to regulatory T cell (Treg)-related immunosuppression and tumor relapse. MATERIALS: To address this issue...
Autores principales: | Domvri, Kalliopi, Petanidis, Savvas, Zarogoulidis, Paul, Anestakis, Doxakis, Charalampidis, Charalampos, Tsavlis, Drosos, Huang, Haidong, Freitag, Lutz, Hohenforst-Schmidt, Wolfgang, Matthaios, Dimitris, Katopodi, Theodora, Porpodis, Konstantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512414/ https://www.ncbi.nlm.nih.gov/pubmed/36172007 http://dx.doi.org/10.2147/IJN.S346341 |
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