Bile acid conjugation deficiency causes hypercholanemia, hyperphagia, islet dysfunction, and gut dysbiosis in mice

Bile acid‐CoA: amino acid N‐acyltransferase (BAAT) catalyzes bile acid conjugation, the last step in bile acid synthesis. BAAT gene mutation in humans results in hypercholanemia, growth retardation, and fat‐soluble vitamin insufficiency. The current study investigated the physiological function of B...

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Detalles Bibliográficos
Autores principales: Alrehaili, Bandar D., Lee, Mikang, Takahashi, Shogo, Novak, Robert, Rimal, Bipin, Boehme, Shannon, Trammell, Samuel A. J., Grevengoed, Trisha J., Kumar, Devendra, Alnouti, Yazen, Chiti, Katya, Wang, Xinwen, Patterson, Andrew D., Chiang, John Y. L., Gonzalez, Frank J., Lee, Yoon‐Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512455/
https://www.ncbi.nlm.nih.gov/pubmed/35866568
http://dx.doi.org/10.1002/hep4.2041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512455/
https://www.ncbi.nlm.nih.gov/pubmed/35866568
http://dx.doi.org/10.1002/hep4.2041

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