Mast cells selectively target large cholangiocytes during biliary injury via H2HR‐mediated cAMP/pERK1/2 signaling

Bile ducts are heterogenous in structure and function, and primary sclerosing cholangitis (PSC) damages specific bile ducts leading to ductular reaction (DR), mast cell (MC) infiltration, increased histamine release, inflammation, and fibrosis. Bile duct ligation (BDL) induces large duct damage via...

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Detalles Bibliográficos
Autores principales: Zhou, Tianhao, Meadows, Vik, Kundu, Debjyoti, Kyritsi, Konstantina, Owen, Travis, Ceci, Ludovica, Carpino, Guido, Onori, Paolo, Gaudio, Eugenio, Wu, Nan, Glaser, Shannon, Ekser, Burcin, Alpini, Gianfranco, Kennedy, Lindsey, Francis, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512472/
https://www.ncbi.nlm.nih.gov/pubmed/35799467
http://dx.doi.org/10.1002/hep4.2026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512472/
https://www.ncbi.nlm.nih.gov/pubmed/35799467
http://dx.doi.org/10.1002/hep4.2026

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