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A Case of Relapsed Primary Central Nervous System Lymphoma Treated with CD19-directed Chimeric Antigen Receptor T Cell Therapy

Although high-dose methotrexate (HD-MTX) is the standard therapy for primary central nervous system lymphoma (PCNSL), the prognosis remains poor. Because 90% of PCNSL is diffuse large B-cell lymphoma (DLBCL), chimeric antigen receptor (CAR)-T cell therapy is expected to be beneficial. However, there...

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Detalles Bibliográficos
Autores principales: MIZUTA, Ryo, OTANI, Yoshihiro, FUJII, Kentaro, UNEDA, Atsuhito, ISHIDA, Joji, TANAKA, Takehiro, IKEGAWA, Shuntaro, FUJII, Nobuharu, MAEDA, Yoshinobu, DATE, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512489/
https://www.ncbi.nlm.nih.gov/pubmed/36238605
http://dx.doi.org/10.2176/jns-nmc.2022-0134