Cargando…

Tyrosine kinase receptor RON activates MAPK/RSK/CREB signal pathway to enhance CXCR4 expression and promote cell migration and invasion in bladder cancer

Bladder cancer (BC) is one of the most lethal malignancies worldwide. The poor survival may be due to a high proportion of tumor metastasis. RON and CXCR4 are the key regulators of cell motility in BC, while the relationship between RON and CXCR4 remains elusive. In the present study, immunohistoche...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Junfeng, Wang, Kejie, Ye, Shazhou, Meng, Xiangyu, Jia, Xiaolong, Huang, Youju, Ma, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512502/
https://www.ncbi.nlm.nih.gov/pubmed/36103228
http://dx.doi.org/10.18632/aging.204279