NOX4 promotes Kupffer cell inflammatory response via ROS-NLRP3 to aggravate liver inflammatory injury in acute liver injury

Aim: This work aimed to investigate the mechanism of NOX4 in promoting Kupffer cells (KCs) activation and tissue inflammatory response in acute liver injury. Methods: Initially, the mouse KCs were cultured in vitro. Thereafter, the NOX4 overexpression plasmid was transfected into KCs to construct th...

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Detalles Bibliográficos
Autores principales: Zhai, Liping, Pei, Hongyan, Yang, Yi, Zhu, Yu, Ruan, Shuiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512511/
https://www.ncbi.nlm.nih.gov/pubmed/35832027
http://dx.doi.org/10.18632/aging.204173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512511/
https://www.ncbi.nlm.nih.gov/pubmed/35832027
http://dx.doi.org/10.18632/aging.204173

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