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The augmin complex architecture reveals structural insights into microtubule branching

In mitosis, the augmin complex binds to spindle microtubules to recruit the γ-tubulin ring complex (γ-TuRC), the principal microtubule nucleator, for the formation of branched microtubules. Our understanding of augmin-mediated microtubule branching is hampered by the lack of structural information o...

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Detalles Bibliográficos
Autores principales: Zupa, Erik, Würtz, Martin, Neuner, Annett, Hoffmann, Thomas, Rettel, Mandy, Böhler, Anna, Vermeulen, Bram J. A., Eustermann, Sebastian, Schiebel, Elmar, Pfeffer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512787/
https://www.ncbi.nlm.nih.gov/pubmed/36163468
http://dx.doi.org/10.1038/s41467-022-33228-6