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Enantioselective synthesis of α-aminoboronates by NiH-catalysed asymmetric hydroamidation of alkenyl boronates

Chiral α-aminoboronic acids and their derivatives are generally useful as bioactive compounds and some have been approved as therapeutic agents. Here we report a NiH-catalysed asymmetric hydroamidation process that with a simple amino alcohol ligand can easily produce a wide range of highly enantioe...

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Detalles Bibliográficos
Autores principales: Zhang, Yao, Qiao, Deyong, Duan, Mei, Wang, You, Zhu, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512809/
https://www.ncbi.nlm.nih.gov/pubmed/36163363
http://dx.doi.org/10.1038/s41467-022-33411-9