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Palladium-catalyzed asymmetric allylic 4-pyridinylation via electroreductive substitution reaction

The enantioselective pyridinylation is important for providing chiral compounds bearing heterocycles of pharmaceutical interests. 4-CN-pyrinde is extensively applied in the radical pyridinylation reaction, however, its’ enantioselective application is highly challenging. To achieve this goal, we pro...

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Detalles Bibliográficos
Autores principales: Ding, Weijie, Li, Mengfan, Fan, Jinkun, Cheng, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512896/
https://www.ncbi.nlm.nih.gov/pubmed/36163325
http://dx.doi.org/10.1038/s41467-022-33452-0