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In vivo metabolic imaging identifies lipid vulnerability in a preclinical model of Her2+/Neu breast cancer residual disease and recurrence

Recurrent cancer cells that evade therapy is a leading cause of death in breast cancer patients. This risk is high for women showing an overexpression of human epidermal growth factor receptor 2 (Her2). Cells that persist can rely on different substrates for energy production relative to their prima...

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Detalles Bibliográficos
Autores principales: Madonna, Megan C., Duer, Joy E., McKinney, Brock J., Sunassee, Enakshi D., Crouch, Brian T., Ilkayeva, Olga, Hirschey, Matthew D., Alvarez, James V., Ramanujam, Nirmala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512922/
https://www.ncbi.nlm.nih.gov/pubmed/36163365
http://dx.doi.org/10.1038/s41523-022-00481-3