High-yield production in Escherichia coli and convenient purification of a candidate vaccine against SARS-CoV-2

OBJECTIVES: The aim of the present work was to identify a time-saving, effective, and low-cost strategy to produce in Escherichia coli a protein chimera representing a fusion anti-SARS-CoV-2 candidate vaccine, consisting of immunogenic and antigenic moieties. RESULTS: We overexpressed in E. coli BL2...

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Detalles Bibliográficos
Autores principales: Maltoni, Giulia, Scutteri, Lorenzo, Mensitieri, Francesca, Piaz, Fabrizio Dal, Hochkoeppler, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512991/
https://www.ncbi.nlm.nih.gov/pubmed/36161539
http://dx.doi.org/10.1007/s10529-022-03298-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512991/
https://www.ncbi.nlm.nih.gov/pubmed/36161539
http://dx.doi.org/10.1007/s10529-022-03298-z

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