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Formulation of Lipid-Free Polymeric Mesoscale Nanoparticles Encapsulating mRNA

INTRODUCTION: Nanoparticle-mediated gene therapy has found substantial clinical impact, primarily focused on lipid-based nanoparticles. In comparison with lipid nanoparticles, polymeric particles may have certain advantages such as increased biocompatibility and controlled release. Our prior studies...

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Detalles Bibliográficos
Autores principales: Skelton, Rachel, Roach, Arantxa, Prudhomme, Lauren E., Cen Feng, Jing Yu Carolina, Gaikwad, Pooja, Williams, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513001/
https://www.ncbi.nlm.nih.gov/pubmed/36163410
http://dx.doi.org/10.1007/s11095-022-03398-5