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Activation of the Nrf2/ARE signaling pathway protects against palmitic acid-induced renal tubular epithelial cell injury by ameliorating mitochondrial reactive oxygen species-mediated mitochondrial dysfunction

Chronic kidney disease (CKD) is often accompanied by dyslipidemia, and abnormal lipid metabolism in proximal tubule cells is considered closely related to the dysfunction of proximal tubule cells and eventually leads to accelerated kidney damage. Nuclear factor E2-related factor 2 (Nrf2), known as a...

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Detalles Bibliográficos
Autores principales: Jiang, Xu-shun, Cai, Meng-yao, Li, Xun-jia, Zhong, Qing, Li, Man-li, Xia, Yun-feng, Shen, Qing, Du, Xiao-gang, Gan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513042/
https://www.ncbi.nlm.nih.gov/pubmed/36177332
http://dx.doi.org/10.3389/fmed.2022.939149