Olaparib synergizes with arsenic trioxide by promoting apoptosis and ferroptosis in platinum-resistant ovarian cancer

Poly (ADP-ribose) polymerase (PARP) inhibitors are efficacious in treating platinum-sensitive ovarian cancer (OC), but demonstrate limited efficiency in patients with platinum-resistant OC. Thus, further investigations into combined strategies that enhance the response to PARP inhibitors (PARPi) in...

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Detalles Bibliográficos
Autores principales: Tang, Sangsang, Shen, Yuanming, Wei, Xinyi, Shen, Zhangjin, Lu, Weiguo, Xu, Junfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513087/
https://www.ncbi.nlm.nih.gov/pubmed/36163324
http://dx.doi.org/10.1038/s41419-022-05257-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513087/
https://www.ncbi.nlm.nih.gov/pubmed/36163324
http://dx.doi.org/10.1038/s41419-022-05257-y

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