The Golgi-localized sphingosine-1-phosphate phosphatase is indispensable for Leishmania major

Sphingosine-1-phosphate phosphatase (SPP) catalyzes the dephosphorylation of sphingosine-1-phosphate (S1P) into sphingosine, the reverse reaction of sphingosine kinase. In mammals, S1P acts as a potent bioactive molecule regulating cell proliferation, migration, and immunity. In Leishmania, S1P prod...

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Detalles Bibliográficos
Autores principales: Okundaye, Brian, Biyani, Neha, Moitra, Samrat, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513092/
https://www.ncbi.nlm.nih.gov/pubmed/36163400
http://dx.doi.org/10.1038/s41598-022-20249-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513092/
https://www.ncbi.nlm.nih.gov/pubmed/36163400
http://dx.doi.org/10.1038/s41598-022-20249-w

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