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The Golgi-localized sphingosine-1-phosphate phosphatase is indispensable for Leishmania major
Sphingosine-1-phosphate phosphatase (SPP) catalyzes the dephosphorylation of sphingosine-1-phosphate (S1P) into sphingosine, the reverse reaction of sphingosine kinase. In mammals, S1P acts as a potent bioactive molecule regulating cell proliferation, migration, and immunity. In Leishmania, S1P prod...
Autores principales: | Okundaye, Brian, Biyani, Neha, Moitra, Samrat, Zhang, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513092/ https://www.ncbi.nlm.nih.gov/pubmed/36163400 http://dx.doi.org/10.1038/s41598-022-20249-w |
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