Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation

Human sideroflexin 2 (SFXN2) belongs to the SFXN protein family, which is a mitochondrial outer membrane protein involved in mitochondrial iron metabolism. Mitochondria are indispensable for cellular energy production and iron metabolism. However, it remains elusive how SFXN2 modulates mitochondrial...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Qian, Jinjun, Ding, Pinggang, Wang, Wang, Li, Xinying, Tang, Xiaozhu, Tang, Chao, Yang, Ye, Gu, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513108/
https://www.ncbi.nlm.nih.gov/pubmed/36163342
http://dx.doi.org/10.1038/s41419-022-05272-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513108/
https://www.ncbi.nlm.nih.gov/pubmed/36163342
http://dx.doi.org/10.1038/s41419-022-05272-z

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