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Supplementation with uric and ascorbic acid protects stored red blood cells through enhancement of non-enzymatic antioxidant activity and metabolic rewiring

Redox imbalance and oxidative stress have emerged as generative causes of the structural and functional degradation of red blood cells (RBC) that happens during their hypothermic storage at blood banks. The aim of the present study was to examine whether the antioxidant enhancement of stored RBC uni...

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Detalles Bibliográficos
Autores principales: Tzounakas, Vassilis L., Anastasiadi, Alkmini T., Arvaniti, Vasiliki-Zoi, Lelli, Veronica, Fanelli, Giuseppina, Paronis, Efthymios C., Apostolidou, Anastasia C., Balafas, Evangelos G., Kostomitsopoulos, Nikolaos G., Papageorgiou, Effie G., Papassideri, Issidora S., Stamoulis, Konstantinos, Kriebardis, Anastasios G., Rinalducci, Sara, Antonelou, Marianna H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513173/
https://www.ncbi.nlm.nih.gov/pubmed/36155342
http://dx.doi.org/10.1016/j.redox.2022.102477