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Multi-functional BST2/tetherin against HIV-1, other viruses and LINE-1

Bone marrow stromal cell antigen 2 (BST2), also known as CD317, HM1.24, or tetherin, is a type II transmembrane glycoprotein. Its expression is induced by IFN-I, and it initiates host immune responses by directly trapping enveloped HIV-1 particles onto the cell surface. This antagonistic mechanism t...

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Detalles Bibliográficos
Autores principales: Zhao, Yifei, Zhao, Ke, Wang, Shaohua, Du, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513188/
https://www.ncbi.nlm.nih.gov/pubmed/36176574
http://dx.doi.org/10.3389/fcimb.2022.979091