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Lactacystin-induced kidney fibrosis: Protection by melatonin and captopril

Lactacystin is a specific proteasome inhibitor that blocks the hydrolysis of intracellular proteins by ubiquitin/proteasome system inhibition. The administration of lactacystin to rats induced hypertension and remodeling of the left ventricle and aorta. This study tested whether lactacystin induces...

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Detalles Bibliográficos
Autores principales: Repova, Kristina, Stanko, Peter, Baka, Tomas, Krajcirovicova, Kristina, Aziriova, Silvia, Hrenak, Jaroslav, Barta, Andrej, Zorad, Stefan, Reiter, Russel J., Adamcova, Michaela, Simko, Fedor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513205/
https://www.ncbi.nlm.nih.gov/pubmed/36176443
http://dx.doi.org/10.3389/fphar.2022.978337