Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway

Cartilage endplate (CEP) plays important roles in the onset and progression of intervertebral disc degeneration (IVDD). Icariin (ICA) is the major active ingredient of Herba Epimedii and has various biological activities such as anti-inflammatory and antioxidant, which is used to treat many degenera...

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Detalles Bibliográficos
Autores principales: Shao, Yuandong, Sun, Lei, Yang, Guihe, Wang, Wenchao, Liu, Xiaoyang, Du, Ting, Chen, Feifei, Jing, Xingzhi, Cui, Xingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513224/
https://www.ncbi.nlm.nih.gov/pubmed/36176424
http://dx.doi.org/10.3389/fphar.2022.937502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513224/
https://www.ncbi.nlm.nih.gov/pubmed/36176424
http://dx.doi.org/10.3389/fphar.2022.937502

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