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Peptide OM-LV20 protects astrocytes against oxidative stress via the ‘PAC1R/JNK/TPH1’ axis

Stroke can lead to severe nerve injury and debilitation, resulting in considerable social and economic burdens. Due to the high complexity of post-injury repair mechanisms, drugs approved for use in stroke are extremely scarce, and thus, the discovery of new antistroke drugs and targets is critical....

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Detalles Bibliográficos
Autores principales: Yin, Saige, Pang, Ailan, Liu, Chengxing, Li, Yilin, Liu, Naixin, Li, Shanshan, Li, Chao, Sun, Huilin, Fu, Zhe, Wang, Yinglei, Zhang, Yue, Yang, Meifeng, Sun, Jun, Wang, Ying, Yang, Xinwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513268/
https://www.ncbi.nlm.nih.gov/pubmed/36037970
http://dx.doi.org/10.1016/j.jbc.2022.102429