Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1

Mechanistic target of rapamycin (mTOR) complex 2 (mTORC2) regulates metabolism, cell proliferation, and cell survival. mTORC2 activity is stimulated by growth factors, and it phosphorylates the hydrophobic motif site of the AGC kinases AKT, SGK, and PKC. However, the proteins that interact with mTOR...

Descripción completa

Detalles Bibliográficos
Autores principales: Luciano, Amelia K., Korobkina, Ekaterina D., Lyons, Scott P., Haley, John A., Fluharty, Shelagh M., Jung, Su Myung, Kettenbach, Arminja N., Guertin, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513271/
https://www.ncbi.nlm.nih.gov/pubmed/35973513
http://dx.doi.org/10.1016/j.jbc.2022.102379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513271/
https://www.ncbi.nlm.nih.gov/pubmed/35973513
http://dx.doi.org/10.1016/j.jbc.2022.102379

Ejemplares similares