Cargando…
Prophylactic administration of miR-451 inhibitor decreases osteoarthritis severity in rats
Transfection of chondrocytes with microRNA-451(miR-451), present in growth zone cartilage of the growth plate, upregulates production of enzymes association with extracellular matrix degradation. miR-451 is also present in articular cartilage and exacerbates IL-1β effects in articular chondrocytes....
Autores principales: | Scott, Kayla M., Cohen, D. Joshua, Nielson, Dane W., Kim, Gloria, Olson, Lucas C., McClure, Michael J., Grinstaff, Mark W., Boyan, Barbara D., Schwartz, Zvi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513290/ https://www.ncbi.nlm.nih.gov/pubmed/36167718 http://dx.doi.org/10.1038/s41598-022-20415-0 |
Ejemplares similares
-
Advanced Glycation End Products Are Retained in Decellularized Muscle Matrix Derived from Aged Skeletal Muscle
por: Olson, Lucas C., et al.
Publicado: (2021) -
RNU (Foxn1(RNU)-Nude) Rats Demonstrate an Improved Ability to Regenerate Muscle in a Volumetric Muscle Injury Compared to Sprague Dawley Rats
por: McClure, Michael J., et al.
Publicado: (2021) -
Advanced Glycation End-Products in Skeletal Muscle Aging
por: Olson, Lucas C., et al.
Publicado: (2021) -
Osseointegration of Titanium Implants in a Botox-Induced Muscle Paralysis Rat Model Is Sensitive to Surface Topography and Semaphorin 3A Treatment
por: Deng, Jingyao, et al.
Publicado: (2023) -
miR‐122 and the WNT/β‐catenin pathway inhibit effects of both interleukin‐1β and tumor necrosis factor‐α in articular chondrocytes in vitro
por: Scott, Kayla M., et al.
Publicado: (2022)