Central administration of human opiorphin alleviates dextran sodium sulfate-induced colitis in mice through activation of the endogenous opioid system

The opioid system plays a crucial role in maintaining gastrointestinal homeostasis. Endogenous opioid peptide enkephalins have anti-inflammatory effect and participate in the treatment of inflammatory bowel diseases (IBDs). Here, we investigated the effect of natural enkephalinase inhibitor human op...

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Detalles Bibliográficos
Autores principales: Luo, Pan, Li, Xuelin, Gao, Yuan, Chen, Zhengjun, Zhang, Quanwei, Wang, Zhimin, Tian, Xiaozhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513434/
https://www.ncbi.nlm.nih.gov/pubmed/36176442
http://dx.doi.org/10.3389/fphar.2022.904926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513434/
https://www.ncbi.nlm.nih.gov/pubmed/36176442
http://dx.doi.org/10.3389/fphar.2022.904926

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