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An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβ blockade therapy

Increasing evidence suggests that the presence and spatial localization and distribution pattern of tumor infiltrating lymphocytes (TILs) is associate with response to immunotherapies. Recent studies have identified TGFβ activity and signaling as a determinant of T cell exclusion in the tumor microe...

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Detalles Bibliográficos
Autores principales: Pomponio, Robert, Tang, Qi, Mei, Anthony, Caron, Anne, Coulibaly, Bema, Theilhaber, Joachim, Rogers-Grazado, Maximilian, Sanicola-Nadel, Michele, Naimi, Souad, Olfati-Saber, Reza, Combeau, Cecile, Pollard, Jack, Lin, Tun Tun, Wang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513441/
https://www.ncbi.nlm.nih.gov/pubmed/36176910
http://dx.doi.org/10.1016/j.apsb.2022.03.013