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Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease

Metabolic-associated fatty liver disease (MAFLD), which is previously known as non-alcoholic fatty liver disease (NAFLD), represents a major health concern worldwide with limited therapy. Here, we provide evidence that ferroptosis, a novel form of regulated cell death characterized by iron-driven li...

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Detalles Bibliográficos
Autores principales: Tong, Jie, Li, Dongjie, Meng, Hongbo, Sun, Diyang, Lan, Xiuting, Ni, Min, Ma, Jiawei, Zeng, Feiyan, Sun, Sijia, Fu, Jiangtao, Li, Guoqiang, Ji, Qingxin, Zhang, Guoyan, Shen, Qirui, Wang, Yuanyuan, Zhu, Jiahui, Zhao, Yi, Wang, Xujie, Liu, Yi, Ouyang, Shenxi, Sheng, Chunquan, Shen, Fuming, Wang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513461/
https://www.ncbi.nlm.nih.gov/pubmed/36176906
http://dx.doi.org/10.1016/j.apsb.2022.02.003