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Human differentiated eosinophils release IL-13 in response to IL-33 stimulation

OBJECTIVE: Eosinophils are hallmarks in allergic type 2 inflammation and are known to release cytotoxic granule proteins that contribute to inflammation. Eosinophils develop in the bone marrow from hematopoietic stem cells and once mature, have a limited lifespan in culture, making them difficult to...

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Detalles Bibliográficos
Autores principales: Uchida, Amiko M., Ro, Gabrielle, Qiang, Li, Peterson, Kathryn A., Round, June, Dougan, Michael, Dougan, Stephanie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513478/
https://www.ncbi.nlm.nih.gov/pubmed/36177009
http://dx.doi.org/10.3389/fimmu.2022.946643