Molecular glues modulate protein functions by inducing protein aggregation: A promising therapeutic strategy of small molecules for disease treatment

Molecular glues can specifically induce aggregation between two or more proteins to modulate biological functions. In recent years, molecular glues have been widely used as protein degraders. In addition, however, molecular glues play a variety of vital roles, such as complex stabilization, interact...

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Detalles Bibliográficos
Autores principales: Wu, Hongyu, Yao, Hong, He, Chen, Jia, Yilin, Zhu, Zheying, Xu, Shengtao, Li, Dahong, Xu, Jinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513498/
https://www.ncbi.nlm.nih.gov/pubmed/36176907
http://dx.doi.org/10.1016/j.apsb.2022.03.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513498/
https://www.ncbi.nlm.nih.gov/pubmed/36176907
http://dx.doi.org/10.1016/j.apsb.2022.03.019

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