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LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with unknown etiology and limited therapeutic options. Activation of fibroblasts is a prominent feature of pulmonary fibrosis. Here we report that lncRNA DACH1 (dachshund homolog 1) is downregulated in the lungs of IPF patients and in an e...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Jin, Tongzhu, Niu, Zhihui, Guo, Jiayu, Guo, Yingying, Yang, Ruoxuan, Wang, Qianqian, Gao, Huiying, Zhang, Yuhan, Li, Tianyu, He, Wenxin, Li, Zhixin, Ma, Wenchao, Su, Wei, Li, Liangliang, Fan, Xingxing, Shan, Hongli, Liang, Haihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513499/
https://www.ncbi.nlm.nih.gov/pubmed/36176913
http://dx.doi.org/10.1016/j.apsb.2022.04.006