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OxLDL induces the release of IL-1β from primed human endothelial and smooth muscle cells via different caspase -1-dependent mechanisms

Atherosclerosis is characterised by abnormal lipid and cell accumulation within arterial layers that leads to disturbed blood flow. Modified cholesterol forms such as oxidised low-density lipoprotein (oxLDL) enter cells altering their phenotype, triggering over-exuberant repair and arterial occlusio...

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Detalles Bibliográficos
Autores principales: Almansouri, Majid, Patel, Pooja, Chamberlain, Janet, Francis, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513632/
https://www.ncbi.nlm.nih.gov/pubmed/35994001
http://dx.doi.org/10.1530/VB-22-0009