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No evidence for age-related differences in mitochondrial RNA quality in the female germline

GRAPHICAL ABSTRACT: [Image: see text] ABSTRACT: Mitochondrial quality is implicated as a contributor to declining fertility with aging. We investigated mitochondrial transcripts in oocytes and their associated cumulus cells from mice of different ages using RNA-seq. Mice aged 3 weeks, 9 weeks, and 1...

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Detalles Bibliográficos
Autores principales: Hartley, Fiona, Alageel, Arwa, Appeltant, Ruth, Gray, Nicki, Repapi, Emmanouela, Wells, Dagan, Williams, Suzannah A, Poulton, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513661/
https://www.ncbi.nlm.nih.gov/pubmed/36001349
http://dx.doi.org/10.1530/RAF-22-0025