Timed Notch Inhibition Drives Photoreceptor Fate Specification in Human Retinal Organoids

PURPOSE: Transplanting photoreceptors from human pluripotent stem cell–derived retinal organoids have the potential to reverse vision loss in affected individuals. However, transplantable photoreceptors are only a subset of all cells in the organoids. Hence, the goal of our current study was to acce...

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Detalles Bibliográficos
Autores principales: Chew, Shereen H., Martinez, Cassandra, Chirco, Kathleen R., Kandoi, Sangeetha, Lamba, Deepak A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513742/
https://www.ncbi.nlm.nih.gov/pubmed/36129723
http://dx.doi.org/10.1167/iovs.63.10.12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513742/
https://www.ncbi.nlm.nih.gov/pubmed/36129723
http://dx.doi.org/10.1167/iovs.63.10.12

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