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SFPQ promotes RAS-mutant cancer cell growth by modulating 5′-UTR mediated translational control of CK1α

Oncogenic mutations in the RAS family of small GTPases are commonly found in human cancers and they promote tumorigenesis by altering gene expression networks. We previously demonstrated that Casein Kinase 1α (CK1α), a member of the CK1 family of serine/threonine kinases, is post-transcriptionally u...

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Detalles Bibliográficos
Autores principales: Kok, Venetia Jing Tong, Tang, Jia Ying, Eng, Gracie Wee Ling, Tan, Shin Yi, Chin, Joseph Tin Foong, Quek, Chun Hian, Lai, Wei Xuan, Lim, Teck Kwang, Lin, Qingsong, Chua, John Jia En, Cheong, Jit Kong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513841/
https://www.ncbi.nlm.nih.gov/pubmed/36177382
http://dx.doi.org/10.1093/narcan/zcac027