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Gentamicin promoted the production of CD4(+)CD25(+) Tregs via the STAT5 signaling pathway in mice sepsis

BACKGROUND: Increasing studies have reported that gentamicin (GNT) plays an essential role in sepsis; however, its underlying mechanism is still unclear. In this study, we investigated the mechanism of GNT in sepsis. RESULTS: We observed that GNT enhanced survival and alleviated inflammatory injurie...

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Detalles Bibliográficos
Autores principales: Li, Jinfeng, Xu, Fengdan, Li, Song, Xie, Mingyu, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513864/
https://www.ncbi.nlm.nih.gov/pubmed/36162982
http://dx.doi.org/10.1186/s12865-022-00521-4