Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability

BACKGROUND: Melatonin, a natural hormone secreted by the pineal gland, has been reported to exhibit antitumor properties through diverse mechanisms of action. However, the oncostatic function of melatonin on esophageal squamous cell carcinoma (ESCC) remains elusive. This study was conducted to inves...

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Detalles Bibliográficos
Autores principales: Ma, Zhi-Qiang, Feng, Ying-Tong, Guo, Kai, Liu, Dong, Shao, Chang-Jian, Pan, Ming-Hong, Zhang, Yi-Meng, Zhang, Yu-Xi, Lu, Di, Huang, Di, Zhang, Fan, Wang, Jin-Liang, Yang, Bo, Han, Jing, Yan, Xiao-Long, Hu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513894/
https://www.ncbi.nlm.nih.gov/pubmed/36163081
http://dx.doi.org/10.1186/s40779-022-00412-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513894/
https://www.ncbi.nlm.nih.gov/pubmed/36163081
http://dx.doi.org/10.1186/s40779-022-00412-0

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