Cargando…
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability
BACKGROUND: Melatonin, a natural hormone secreted by the pineal gland, has been reported to exhibit antitumor properties through diverse mechanisms of action. However, the oncostatic function of melatonin on esophageal squamous cell carcinoma (ESCC) remains elusive. This study was conducted to inves...
Autores principales: | Ma, Zhi-Qiang, Feng, Ying-Tong, Guo, Kai, Liu, Dong, Shao, Chang-Jian, Pan, Ming-Hong, Zhang, Yi-Meng, Zhang, Yu-Xi, Lu, Di, Huang, Di, Zhang, Fan, Wang, Jin-Liang, Yang, Bo, Han, Jing, Yan, Xiao-Long, Hu, Yi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513894/ https://www.ncbi.nlm.nih.gov/pubmed/36163081 http://dx.doi.org/10.1186/s40779-022-00412-0 |
Ejemplares similares
-
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway
por: Guo, Kai, et al.
Publicado: (2022) -
HDAC7/c-Myc signaling pathway promotes the proliferation and metastasis of choroidal melanoma cells
por: Zhang, Yimeng, et al.
Publicado: (2023) -
HDAC7‐mediated control of tumour microenvironment maintains proliferative and stemness competence of human mammary epithelial cells
por: Cutano, Valentina, et al.
Publicado: (2019) -
Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis
por: Li, Song, et al.
Publicado: (2011) -
The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma
por: Barneda-Zahonero, B, et al.
Publicado: (2015)