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Ultrastructural characterization of dark microglia during aging in a mouse model of Alzheimer’s disease pathology and in human post-mortem brain samples
A diverse heterogeneity of microglial cells was previously described in Alzheimer’s disease (AD) pathology, including dark microglia, a state characterized by ultrastructural markers of cellular stress. To provide novel insights into the roles of dark microglia during aging in the context of AD path...
Autores principales: | St-Pierre, Marie-Kim, Carrier, Micaël, González Ibáñez, Fernando, Šimončičová, Eva, Wallman, Marie-Josée, Vallières, Luc, Parent, Martin, Tremblay, Marie-Ève |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513936/ https://www.ncbi.nlm.nih.gov/pubmed/36167544 http://dx.doi.org/10.1186/s12974-022-02595-8 |
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