Repositioning small molecule drugs as allosteric inhibitors of the BFT‐3 toxin from enterotoxigenic Bacteroides fragilis

Bacteroides fragilis is an abundant commensal component of the healthy human colon. However, under dysbiotic conditions, enterotoxigenic B. fragilis (ETBF) may arise and elicit diarrhea, anaerobic bacteremia, inflammatory bowel disease, and colorectal cancer. Most worrisome, ETBF is resistant to man...

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Detalles Bibliográficos
Autores principales: Jimenez‐Alesanco, Ana, Eckhard, Ulrich, Asencio del Rio, Marta, Vega, Sonia, Guevara, Tibisay, Velazquez‐Campoy, Adrian, Gomis‐Rüth, Francesc Xavier, Abian, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514063/
https://www.ncbi.nlm.nih.gov/pubmed/36173175
http://dx.doi.org/10.1002/pro.4427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514063/
https://www.ncbi.nlm.nih.gov/pubmed/36173175
http://dx.doi.org/10.1002/pro.4427

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