Cargando…

Repositioning small molecule drugs as allosteric inhibitors of the BFT‐3 toxin from enterotoxigenic Bacteroides fragilis

Bacteroides fragilis is an abundant commensal component of the healthy human colon. However, under dysbiotic conditions, enterotoxigenic B. fragilis (ETBF) may arise and elicit diarrhea, anaerobic bacteremia, inflammatory bowel disease, and colorectal cancer. Most worrisome, ETBF is resistant to man...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jimenez‐Alesanco, Ana, Eckhard, Ulrich, Asencio del Rio, Marta, Vega, Sonia, Guevara, Tibisay, Velazquez‐Campoy, Adrian, Gomis‐Rüth, Francesc Xavier, Abian, Olga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Full‐length Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514063/ https://www.ncbi.nlm.nih.gov/pubmed/36173175 http://dx.doi.org/10.1002/pro.4427

Ejemplares similares

Monoclonal antibodies specific for Bacteroides fragilis enterotoxins BFT1 and BFT2 and their use in immunoassays
por: Mootien, Saraspadee, et al.
Publicado: (2017)

Genomic Diversity of Enterotoxigenic Strains of Bacteroides fragilis
por: Pierce, Jessica V., et al.
Publicado: (2016)

Enterotoxigenic and non-enterotoxigenic Bacteroides fragilis from fecal microbiota of children
por: Ignacio, Aline, et al.
Publicado: (2015)

Detection of enterotoxigenic Bacteroides fragilis in patients with ulcerative colitis
por: Zamani, Samin, et al.
Publicado: (2017)

Isolation, Detection, and Characterization of Enterotoxigenic Bacteroides fragilis in Clinical Samples
por: Fathi, Payam, et al.
Publicado: (2016)

Complete Genome Sequence of an Enterotoxigenic Bacteroides fragilis Clinical Isolate
por: Nikitina, Anastasia S., et al.
Publicado: (2015)

Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia
por: Purcell, Rachel V., et al.
Publicado: (2017)

Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis
por: Purcell, Rachel V., et al.
Publicado: (2016)

2611. Enterotoxigenic Bacteroides fragilis Alters the Genome of Colon Epithelial Cells
por: Allen, Jawara, et al.
Publicado: (2019)

Prevalence of pks + bacteria and enterotoxigenic Bacteroides fragilis in patients with colorectal cancer
por: Oliero, Manon, et al.
Publicado: (2022)

The Myeloid Immune Signature of Enterotoxigenic Bacteroides Fragilis-Induced Murine Colon Tumorigenesis
por: Orberg, Erik Thiele, et al.
Publicado: (2016)

Enterotoxigenic Bacteroides fragilis infection exacerbates tumorigenesis in AOM/DSS mouse model
por: Hwang, Soonjae, et al.
Publicado: (2020)

Recombinant Bacteroides fragilis enterotoxin-1 (rBFT-1) promotes proliferation of colorectal cancer via CCL3-related molecular pathways
por: Xie, Xiaoliang, et al.
Publicado: (2021)

Designing a multi-epitopic vaccine against the enterotoxigenic Bacteroides fragilis based on immunoinformatics approach
por: Majid, Mahnoor, et al.
Publicado: (2019)

In Vitro Evaluation of the Therapeutic Potential of Phage VA7 against Enterotoxigenic Bacteroides fragilis Infection
por: Bakuradze, Nata, et al.
Publicado: (2021)

Role of Enterotoxigenic Bacteroides fragilis in Children Less Than 5 Years of Age With Diarrhea in Tabriz, Iran
por: Akhi, Mohammad Taghi, et al.
Publicado: (2016)

Enterotoxigenic Bacteroides fragilis: A Possible Etiological Candidate for Bacterially-Induced Colorectal Precancerous and Cancerous Lesions
por: Zamani, Samin, et al.
Publicado: (2020)

Enterotoxigenic Bacteroides fragilis activates IL-8 expression through Stat3 in colorectal cancer cells
por: Purcell, Rachel V., et al.
Publicado: (2022)

Case-Control Study on the Role of Enterotoxigenic Bacteroides fragilis as a Cause of Diarrhea among Children in Kolkata, India
por: Ramamurthy, Dharanidharan, et al.
Publicado: (2013)

Enterotoxigenic Bacteroides fragilis induces the stemness in colorectal cancer via upregulating histone demethylase JMJD2B
por: Liu, Qian-Qian, et al.
Publicado: (2020)

Dietary Salt Administration Decreases Enterotoxigenic Bacteroides fragilis (ETBF)-Promoted Tumorigenesis via Inhibition of Colonic Inflammation
por: Hwang, Soonjae, et al.
Publicado: (2020)

Zerumbone Suppresses Enterotoxigenic Bacteroides fragilis Infection-Induced Colonic Inflammation through Inhibition of NF-κΒ
por: Hwang, Soonjae, et al.
Publicado: (2019)

Prevalence and antimicrobial susceptibility of enterotoxigenic extra-intestinal Bacteroides fragilis among 13-year collection of isolates in Kuwait
por: Jamal, Wafaa, et al.
Publicado: (2020)

High frequency of enterotoxigenic Bacteroides fragilis and Enterococcus faecalis in the paraffin-embedded tissues of Iranian colorectal cancer patients
por: Khodaverdi, Nasibeh, et al.
Publicado: (2021)

Evaluation of enterotoxigenic Bacteroides fragilis correlation with the expression of cellular signaling pathway genes in Iranian patients with colorectal cancer
por: Dadgar-Zankbar, Leila, et al.
Publicado: (2023)

Interaction of Bacteroides fragilis and Bacteroides thetaiotaomicron with the kallikrein–kinin system
por: Murphy, Elizabeth C., et al.
Publicado: (2011)

Protective Effects of Zerumbone on Colonic Tumorigenesis in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized AOM/DSS BALB/c Mice
por: Hwang, Soonjae, et al.
Publicado: (2020)

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
por: Boleij, Annemarie, et al.
Publicado: (2021)

Allosteric Inhibitors of the NS3 Protease from the Hepatitis C Virus
por: Abian, Olga, et al.
Publicado: (2013)

Fecal Enterotoxigenic Bacteroides fragilis–Peptostreptococcus stomatis–Parvimonas micra Biomarker for Noninvasive Diagnosis and Prognosis of Colorectal Laterally Spreading Tumor
por: Shen, Xiaonan, et al.
Publicado: (2021)

Cellular immunity to Bacteroides fragilis capsular polysaccharide
Publicado: (1982)

Emergence of metronidazole-resistant Bacteroides fragilis, India.
por: Chaudhry, R, et al.
Publicado: (2001)

Bacteroides fragilis metabolises exopolysaccharides produced by bifidobacteria
por: Rios-Covian, David, et al.
Publicado: (2016)

Bacterial Pyomyositis in the Neck Due to Bacteroides Fragilis
por: Dalal, Kajal, et al.
Publicado: (2021)

Early intestinal Bacteroides fragilis colonisation and development of asthma
por: Vael, Carl, et al.
Publicado: (2008)

Multidrug-Resistant Bacteroides fragilis — Seattle, Washington, 2013
por: Kalapila, Aley, et al.
Publicado: (2013)

Bacteroides fragilis Lipopolysaccharide and Inflammatory Signaling in Alzheimer’s Disease
por: Lukiw, Walter J.
Publicado: (2016)

Safety Evaluation of a Novel Strain of Bacteroides fragilis
por: Wang, Ye, et al.
Publicado: (2017)

Analysis of Bacteroides fragilis Clinical Strains Isolated in Kazakhstan
por: Zholdybayeva, Elena, et al.
Publicado: (2021)

Strain diversity in the microbiome: Lessons from Bacteroides fragilis
por: Carrow, Hannah C., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_74u3bekba9he61f4hg5taiqqab