Thermodynamic coupling between neighboring binding sites in homo‐oligomeric ligand sensing proteins from mass resolved ligand‐dependent population distributions

Homo‐oligomeric ligand‐activated proteins are ubiquitous in biology. The functions of such molecules are commonly regulated by allosteric coupling between ligand‐binding sites. Understanding the basis for this regulation requires both quantifying the free energy ΔG transduced between sites, and the...

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Detalles Bibliográficos
Autores principales: Li, Weicheng, Norris, Andrew S., Lichtenthal, Katie, Kelly, Skyler, Ihms, Elihu C., Gollnick, Paul, Wysocki, Vicki H., Foster, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514064/
https://www.ncbi.nlm.nih.gov/pubmed/36173171
http://dx.doi.org/10.1002/pro.4424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514064/
https://www.ncbi.nlm.nih.gov/pubmed/36173171
http://dx.doi.org/10.1002/pro.4424

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