Dearomative gem-diprenylation of hydroxynaphthalenes by an engineered fungal prenyltransferase

Prenylation usually improves structural diversity and bioactivity in natural products. Unlike the discovered enzymatic gem-diprenylation of mono- and tri-cyclic aromatic systems, the enzymatic approach for gem-diprenylation of bi-cyclic hydroxynaphthalenes is new to science. Here we report an enzyma...

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Detalles Bibliográficos
Autores principales: Xu, Yuanyuan, Li, Dan, Wang, Wenxuan, Xu, Kangping, Tan, Guishan, Li, Jing, Li, Shu-Ming, Yu, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514087/
https://www.ncbi.nlm.nih.gov/pubmed/36276050
http://dx.doi.org/10.1039/d2ra04837j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514087/
https://www.ncbi.nlm.nih.gov/pubmed/36276050
http://dx.doi.org/10.1039/d2ra04837j

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