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Schisandrin alleviates the cognitive impairment in rats with Alzheimer’s disease by altering the gut microbiota composition to modulate the levels of endogenous metabolites in the plasma, brain, and feces

Schisandrin is one of the main active compounds isolated from the fruit of Schisandrae chinensis Fructus, which is scientifically proven to have beneficial effects on Alzheimer’s disease (AD) treatment at the cellular and whole organism level. However, the oral availability of schisandrin is very lo...

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Detalles Bibliográficos
Autores principales: Zhang, Chengqin, Zhang, Ying, Zhao, Tiantian, Mou, Tingting, Jing, Wang, Chen, Jian, Hao, Wenqian, Gu, Shuo, Cui, Meirong, Sun, Yue, Wei, Binbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514097/
https://www.ncbi.nlm.nih.gov/pubmed/36176456
http://dx.doi.org/10.3389/fphar.2022.888726