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Schisandrin alleviates the cognitive impairment in rats with Alzheimer’s disease by altering the gut microbiota composition to modulate the levels of endogenous metabolites in the plasma, brain, and feces
Schisandrin is one of the main active compounds isolated from the fruit of Schisandrae chinensis Fructus, which is scientifically proven to have beneficial effects on Alzheimer’s disease (AD) treatment at the cellular and whole organism level. However, the oral availability of schisandrin is very lo...
Autores principales: | Zhang, Chengqin, Zhang, Ying, Zhao, Tiantian, Mou, Tingting, Jing, Wang, Chen, Jian, Hao, Wenqian, Gu, Shuo, Cui, Meirong, Sun, Yue, Wei, Binbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514097/ https://www.ncbi.nlm.nih.gov/pubmed/36176456 http://dx.doi.org/10.3389/fphar.2022.888726 |
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