De-risking clinical trial failure through mechanistic simulation

Drug development typically comprises a combination of pre-clinical experimentation, clinical trials, and statistical data-driven analyses. Therapeutic failure in late-stage clinical development costs the pharmaceutical industry billions of USD per year. Clinical trial simulation represents a key der...

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Detalles Bibliográficos
Autores principales: Brown, Liam V, Wagg, Jonathan, Darley, Rachel, van Hateren, Andy, Elliott, Tim, Gaffney, Eamonn A, Coles, Mark C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514113/
https://www.ncbi.nlm.nih.gov/pubmed/36176591
http://dx.doi.org/10.1093/immadv/ltac017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514113/
https://www.ncbi.nlm.nih.gov/pubmed/36176591
http://dx.doi.org/10.1093/immadv/ltac017

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